Open J Psychiatry Allied Sci. 2025 Jan 7. Epub ahead of print.
Dose-dependent mirtazapine-induced hyponatraemia: a case report.
Kauser L, Sutrave RS, YR NH.
Abstract
Mirtazapine is a heterocyclic antidepressant having noradrenergic and serotonergic activity. The pharmacodynamic is similar to selective serotonin reuptake inhibitor (SSRI) and tricyclic antidepressant (TCA). Hyponatraemia with mirtazapine can be seen in elderly population with other comorbidities. We present a rare case of hyponatraemia induced after increasing the dose of mirtazapine in a middle-aged woman, without any medical comorbidities.
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